St. Louis Cardinals vs Pittsburgh Pirates Prediction (Sep 22, 2026) | Predicted Sports
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Upcoming · Tue, Sep 22, 2026 · 6:40 PM ET · PNC Park
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St. Louis Cardinals
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PIT logo
Pittsburgh Pirates
Latest line PIT 58% (no-vig) · O/U 7.5 O 47%
The AI field reports on game day, about three hours before first pitch.